July 2023 - Recent publications

Congrats to Dan, Dipankar, and Nick for their recent papers in Advanced Healthcare Materials, Biomaterials Science, and Biotechnology and Bioengineering, respectively. 

Induced Pluripotent Stem Cell-Derived Extracellular Vesicles Promote Wound Repair in a Diabetic Mouse Model via an Anti-Inflammatory Immunomodulatory Mechanism

Differentiation state and culture conditions impact neural stem/progenitor cell-derived extracellular vesicle bioactivity.

June 2023 - Lab receives funding from MSCRF

Thanks for the support of our work! Read more here: MSCRF funding

April 2023 - Recent publications

Congrats to Eli, Steph, and Dan for their recent papers in ncRNA, Cytotherapy, and Advanced Healthcare Materials, respectively. 

Mesenchymal Stem Cell Culture within Perfusion Bioreactors Incorporating 3D-Printed Scaffolds Enables Improved Extracellular Vesicle Yield with Preserved Bioactivity 

Assessment of anti-inflammatory bioactivity of extracellular vesicles is susceptible to error via media component contamination 

Impact of storage conditions and duration on function of native and cargo-loaded mesenchymal stromal cell extracellular vesicles​

​Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy​

March 2023 - Dan Levy named Ann G. Wylie Dissertation Fellow

Congrats to Dan for yet another award to support his thesis work in 2023-24!

January 2023 - Lab receives new FDA funding

Thanks to the FDA via the University of Maryland CERSI for supporting the lab!

September 2022 - Congrats to Steph Kronstadt on her successful PhD Thesis Defense!

Steph did awesome work over 4 years and is now headed off to Boston as an Innovation Fellow at Novartis!

August 2022 - Emily Powsner awarded NIH T32 Fellowship

Congrats to Emily on being selected for a fellowship position on the NIH Training Grant: Interdisciplinary Training Program in Cardiovascular Disease! This award via the National Heart, Lung, and Blood Institute (NHLBI) will support Emily's work on developing novel approaches to control EV vascularization bioactivity.

July 2022 - Talia Solomon joins the group

Welcome to Talia, a MD/PhD student and Clark Doctoral Fellow!

July 2022 - Dan Levy presents at Gordon Research Conference

Congrats to Dan on for being selected to present at both the Extracellular Vesicles GRS and GRC at Sunday River. 

June 2022 - Congrats and farewell to Eli and Dipankar

We're happy to see Eli and Dipankar moving to the next stage of their careers. Eli will be pursuing postdoctoral training at the Weizmann Institute of Science in Israel while Dipankar will be a research analyst at The Block. Thanks for all your contributions to the lab! 

May 2022 - Dan Levy awarded NIH T32 Fellowship

Congrats to Dan on being selected for a fellowship position on UMD's Host-Pathogen Interactions training grant from the National Institutes of Health! This award via the National Institute of Allergy and Infectious Diseases (NIAID) will support Dan's work on developing therapeutic approaches for sepsis.

April 2022 - Congrats to Dan Levy on his successful PhD Thesis Proposal!

Dan has advanced to PhD candidacy!

April 2022 - Dan Levy awarded Summer Research Fellowship

Congrats to Dan for this award to support his thesis work in 2022!

March 2022 - Steph Kronstadt named Ann G. Wylie Dissertation Fellow

Congrats to Steph for yet another award to support her thesis work in 2022!

February 2022 - Congrats to Dr. Eli Pottash on PhD Thesis Defense!

Eli becomes the fifth PhD student from the lab to successfully defend his thesis, congrats! 

January 2022 - New publication in JBMR

Congrats to Louis on the publication of more of his thesis work on controlled delivery of EVs.

December 2021 - Steph Kronstadt named Mid-Career Clark Doctoral Fellow

Congrats to Steph for this award to support her thesis work in 2022!

November 2021 - Nick Pirolli awarded MPower Graduate Fellowship

Congrats to Nick for this award to support his cross-disciplinary research in creating live bacteria therapeutics for neurotherapy! Thanks to co-sponsor and collaborator Dr. Xiaofeng Jia.

November 2021 - New publication in iScience

Congrats to Dr. Wei Chao for his work investigating the role of miR-146a-5p in innate immunity and sepsis

September 2021 - Welcome Emily and Nick!

Emily Powsner and Nick Pirolli have joined the group as PhD students. 

August 2021 - Lab awarded NIH R21 funding with collaborator Dr. Don DeVoe

This award from NHLBI supports research into novel EV isolation and loading techniques via microfabricated devices!

July 2021 - New publication in Nature Communications

Congrats to Dr. Joao Pedra for his ​work investigating the role of tick EVs in infection

June 2021 - Louis Born awarded NIH F30 Predoctoral Fellowship

Congrats to Louis on this award from NHLBI!

May 2021 - Congrats to Louis Born on PhD Thesis Defense!​

Louis becomes the fourth PhD student from the lab to successfully defend his thesis, congrats! He will head in to the clinic to finish his medical training on the way to his MD/PhD!

April 2021 - New publications

Congrats to Louis, Steph, and incoming PhD student Nick Pirolli for their new papers in Advanced Healthcare Materials, Advanced Therapeutics, and Advanced Biology, respectively. 

Access Louis's paper here: HOTAIR-Loaded Mesenchymal Stem/Stromal Cell Extracellular Vesicles Enhance Angiogenesis and Wound Healing

Access Steph's paper here: Therapeutic Potential of Extracellular Vesicles for Sepsis Treatment

Access Nick's paper here: Bacterial Extracellular Vesicles and the Gut-Microbiota Brain Axis: Emerging Roles in Communication and Potential as Therapeutics

March 2021 - Louis Born awarded AHA Predoctoral Fellowship

Congrats to Louis on this award from the American Heart Association to support his research on EVs for wound repair!

February 2021 - Dan Levy awarded Cosmos Scholar Grant

Congrats to Dan on this award from the Cosmos Club Foundation to support his research on induced pluripotent stem cell EVs!

February 2021 - New publication in TINS

Congrats to Dr. Dipankar Dutta and MD/PhD student Niaz Khan for leading this comprehensive review on the roles and therapeutic potential of EVs in spinal cord injury published in Trends in Neurosciences

January 2021 - Lab receives funding from MIPS program

Thanks to the Maryland Technology Enterprise Institute (Mtech) for supporting our partnership with FiberCell Production Solutions to test engineered extracellular vesicles as wound healing therapeutics through the Maryland Industrial Partnerships (MIPS) program.

November 2020 - Lab alums profiled on BIOE website

Check out the great profiles of some recent lab graduates and current lab members:
Louis Born, MD/PhD student
Dr. Divya Patel, now a senior scientist at Pfizer
Natalie Livingston, now a NSF Graduate Fellow and PhD student in BME at Johns Hopkins
Jinan Oubaid, 2020 BIOE Honors Program graduate 
Vaani Shah, 2020 BIOE Extraordinary Service Award winner

August 2020 - Congrats to Rachel Lee on MS Thesis Defense!​

Rachel becomes the first MS student from the lab to successfully defend her thesis, congrats! She has already secured employment with FZata working on engineered antibody production and we wish her all the best in the future.

 July 2020 - New publication in Bioengineering and Translational Medicine

Congrats to Louis on the publication of his review article on lncRNAs and EVs! This article is featured in the "Futures" special issue of the journal. 

June 2020 - Vaani Shah recognized with Extraordinary Service Award

Congrats to Vaani for her ​outstanding and inspiring efforts to help the community during the pandemic. 

June 2020 - Dipankar Dutta awarded MSCRF Postdoctoral Fellowship

Congrats to Dipankar on being awarded a postdoc fellowship from the Maryland Stem Cell Research Fund to support his work on spinal cord injury therapies!

May 2020 - Stephanie Kronstadt awarded NIH T32 Fellowship

Congrats to Steph on being selected for a fellowship position on UMD's Host-Pathogen Interactions training grant from the National Institutes of Health! This award via the National Institute of Allergy and Infectious Diseases (NIAID) will support Steph's work on developing therapeutic approaches for sepsis.

May 2020 - Lab receives new FDA funding

Thanks to the FDA via the University of Maryland CERSI for supporting the lab!

April 2020 - Congrats to John!

Congrats to lab alum Dr. John Schardt on receiving a NIH F32 Postdoctoral Fellowship to support his work in the lab of Dr. Peter Tessier at the University of Michigan.

March 2020 - Congrats to Eli!

Congrats to Eli Pottash on his successful thesis proposal and advancement to PhD candidacy.

February 2020 - Congrats to Louis!

Congrats to Louis Born on his successful thesis proposal and advancement to PhD candidacy.

January 2020 - New NIH R01 funding via UMMC collaboration

Congrats to PI Dr. Sunjay Kaushal of the University of Maryland Medical Center on his R01 from the National Heart, Lung, and Blood Institute (NHLBI)! As collaborators on this project, our work will focus on purification, drug loading, and delivery of cardiac progenitor cell-derived exosomes to promote heart recovery after cardiac injury.

December 2019 - Congrats Dr. Patel and Dr. Jeyaram!

Congrats to Divya and Anjana; we will follow your careers with great interest!

December 2019 - New publication in Molecular Therapy

Congrats to Dr. Anjana Jeyaram, who led this effort on "Enhanced loading of functional miRNA cargo via pH gradient modification of extracellular vesicles".

September 2019 - Congrats to Dr. Jeyaram! 

Congrats to Anjana for the successful defense of her PhD dissertation and her new position as an Innovation Fellow at Novartis!

September 2019 - Lab receives new NIH RF1 Funding

A joint proposal between lead PI Junfang Wu at UMB and MPI Dr. Jay was funded by NIA! ​​This work will enable study of the role and therapeutic potential of extracellular vesicles in dementia associated with spinal cord injury. 

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