December 2019 - New publication in Molecular Therapy
Congrats to Dr. Anjana Jeyaram, who led this effort on "Enhanced loading of functional miRNA cargo via pH gradient modification of extracellular vesicles". Link to paper forthcoming.
September 2019 - Congrats to Dr. Jeyaram!
Congrats to Anjana for the successful defense of her PhD dissertation and her new position as an Innovation Fellow at Novartis!
September 2019 - Lab receives new NIH RF1 Funding
A joint proposal between lead PI Junfang Wu at UMB and MPI Dr. Jay was funded by NIA! This work will enable study of the role and therapeutic potential of extracellular vesicles in dementia associated with spinal cord injury.
August 2019 - Dan joins the lab
Welcome to Daniel Levy, who joins the lab as a PhD student!
August 2019 - Farewell to Dr. Patel!
Congrats to Divya, who moves on to a Scientist position at RoosterBio where she'll be leading an EV production effort.
August 2019 - Anjali Talasila wins Best Poster award at UMD ResearchFest
Congrats Anjali and mentor Eli Pottash!
June 2019 - Congrats to Dr. Divya Patel!
Divya becomes the second PhD student from the lab to successfully defend her thesis, congrats!
June 2019 - Lab awarded RoosterBio Inc. hMSC Development Grant
May 2019 - Dr. Jay promoted to Associate Professor with tenure
Appointment effective July 1, 2019. Thanks to all the family members, lab members, colleagues, and mentors along the way for making this possible.
May 2019 - Divya wins 3rd place in Dean's Doctoral Research Competition
Congrats to PhD student Divya Patel who was awarded 3rd place in the Dean's Doctoral Research Competition after winning the sole nomination from the Fischell Department of Bioengineering!
May 2019 - Anjana is named a finalist for the University Graduate Student Distinguished Service Award
Congrats to PhD student Anjana Jeyaram who was one of 3 University-wide finalists for the Graduate Student Distinguished Service Award!
April 2019 - Congrats Cristina and Chris!
Congrats to senior undergraduate researchers Cristina Tous and Christopher Kuffner who both will be matriculating at Boston University in the Fall to pursue PhDs in Biomedical Engineering!
April 2019 - New publication
Congrats to John, Madeleine, Jinan, Eli and Sonya on the acceptance of their paper "HER3-Targeted Affibodies with Optimized Formats Reduce Ovarian Cancer Progression in a Mouse Xenograft Model" in AAPS Journal!
March 2019 - New lab members
Welcome to our newest lab members: Dipankar Dutta (Postdoctoral Associate) and Stephanie Kronstadt (PhD Student)!
February 2019 - New awards for Chris and Madeleine
Congrats to senior undergraduate researchers Chris Kuffner and Madeleine Noonan-Shueh for their respective awards:
Fischell Outstanding Citizen Award: Chris Kuffner
MTech ASPIRE Outstanding Research Award: Madeleine Noonan-Shueh
Well deserved recognition for these fantastic students! Thanks also to graduate student Eli Pottash for providing outstanding mentorship to both.
Fischell Outstanding Citizen Award: Chris Kuffner
MTech ASPIRE Outstanding Research Award: Madeleine Noonan-Shueh
Well deserved recognition for these fantastic students! Thanks also to graduate student Eli Pottash for providing outstanding mentorship to both.
February 2019 - New NIH R01 funding
Congrats to PIs Dr. Ian White and Don Devoe of UMD on their new R01 from the National Institute of General Medical Sciences (NIGMS)! We are excited to collaborate on this project to enable extracellular vesicle-based biomarker development via digitized single vesicle analysis.
January 2019 - New NIH R01 funding via UMMC collaboration
Congrats to PIs Dr. Sunjay Kaushal and Peixin Yang of the University of Maryland Medical Center on their new R01 from the National Heart, Lung, and Blood Institute (NHLBI)! As collaborators on this project, our work will focus on purification, drug loading, and delivery of cardiac progenitor cell-derived exosomes to promote heart recovery after cardiac injury.
January 2019 - Eli Pottash awarded NIH T32 Fellowship
Congrats to Eli on being selected for a fellowship position on UMD's Host-Pathogen Interactions training grant from the National Institutes of Health! This award via the National Institute of Allergy and Infectious Diseases (NIAID) will support Eli's work on developing new biomimetic and bioinspired nucleic acid delivery systems.
December 2018 - New publication
Congrats to Eli, Chris, and Madeleine on the acceptance of their review article on protein-based vehicles for biomimetic RNAi delivery in the Journal of Biological Engineering, published as part of a special issue for Emerging Leaders in Biological Engineering!
November 2018 - New publications
Congrats to Divya for her new paper in Acta Biomaterialia, published as part of a special issue on Cell and Tissue Biofabrication!
Also note the new position statement from ISEV on minimal information for studies of extracellular vesicles (MISEV2018)
Also note the new position statement from ISEV on minimal information for studies of extracellular vesicles (MISEV2018)
October 2018 - New publications
Congrats to Tek and Divya for their new papers in Methods in Molecular Biology and Biotechnology Advances, respectively.
Congrats also to our collaborators Dr. Wei Chao and Dr. William Bentley.
Access Tek's paper here: Production of Extracellular Vesicles Loaded with Therapeutic Cargo
Access Divya's paper here: Towards Rationally Designed Biomanufacturing of Therapeutic Extracellular Vesicles: Impact of the Bioproduction Microenvironment
With the Chao group: Circulating plasma extracellular vesicles from septic mice induce inflammation via miRNA- and TLR7-dependent mechanisms
With the Bentley group: Genetically Engineered Bacteria as Vehicles for Localized Delivery of Therapeutics: An Application for Crohn’s Disease
Congrats also to our collaborators Dr. Wei Chao and Dr. William Bentley.
Access Tek's paper here: Production of Extracellular Vesicles Loaded with Therapeutic Cargo
Access Divya's paper here: Towards Rationally Designed Biomanufacturing of Therapeutic Extracellular Vesicles: Impact of the Bioproduction Microenvironment
With the Chao group: Circulating plasma extracellular vesicles from septic mice induce inflammation via miRNA- and TLR7-dependent mechanisms
With the Bentley group: Genetically Engineered Bacteria as Vehicles for Localized Delivery of Therapeutics: An Application for Crohn’s Disease
August 2018 - Rachel joins the group
Welcome to Rachel Lee, a MS student working on EV biomanufacturing!
July 2018 - Anjana wins BMES Career Development Award
Congrats to Anjana Jeyaram for being selected for a 2018 BMES Career Development Award, which provides a complimentary registration to the 2018 BMES Annual Meeting and a travel stipend! Anjana will be presenting her work on enhancing the therapeutic efficacy of extracellular vesicles via co-loading of miRNA cargo.
July 2018 - Divya wins BMES Travel Award
Congrats to Divya Patel for being selected for a podium presentation and winning a Student Travel Award to the BMES Annual Meeting in Atlanta in October!
June 2018 - Louis joins the lab
Welcome to Louis Born, a MD/PhD student starting his PhD phase in the lab this summer with a prestigious A. James Clark Doctoral Fellowship!
June 2018 - Anjana wins Best Poster award at World Preclinical Congress
Congrats to Anjana Jeyaram for winning the judges' award for Best Poster at the 2018 World Preclinical Congress!
June 2018 - John departs for U. Michigan
Dr. John Schardt leaves for his postdoc with Dr. Peter Tessier at the University of Michigan. He will be missed!
May 2018 - John wins 2nd prize in Dean's Doctoral Research Award Competition
Congrats to Dr. John Schardt for placing 2nd in the Clark School Dean's Doctoral Research Award Competition. John was the sole nominee from Bioengineering and received a $1000 prize for his efforts. Great job!
May 2018 - Congrats to senior Capstone students!
Lab undergrads Natalie Livingston and Sonya Williams successfully completed their senior Capstone project presentations. Here's Natalie modeling her team's project...the newest addition to the Ironman suit?
April 2018 - Madeleine Noonan-Shueh awarded ASPIRE Fellowship for Summer 2018
This award will enable Madeleine to continue her protein therapeutics work in the lab. Congrats!
April 2018 - Dr. Jay named UMD Graduate Faculty Mentor of the Year
Thanks to all of the graduate students in the lab for the nomination.
April 2018 - Successful BIOE Honors Thesis Defenses
Congrats to Sonya Williams and Natalie Livingston for their successful defenses of their BIOE Honors Theses!
April 2018 - Congrats Dr. John Schardt!
John becomes the first PhD recipient from the lab, and all he had to do was design, express, purify, and test ~25 different proteins. Congrats!
April 2018 - Lab research recognized with CDMRP PRMRP funding recommendation
Thanks to the CDMRP Peer-Reviewed Medical Research Program for the recognition of our efforts to develop EV-based treatments for diabetic wounds.
April 2018 - Natalie Livingston awarded NSF Graduate Fellowship; Eli Pottash receives Honorable Mention
Congrats to Natalie and Eli! UMD News Article
Congrats also to Natalie who has decided to pursue a PhD in Biomedical Engineering at Johns Hopkins University!
Congrats also to Natalie who has decided to pursue a PhD in Biomedical Engineering at Johns Hopkins University!
March 2018 - Lab moves to A. James Clark Hall
We're excited for our new space in Rm 3113 of the recently opened A. James Clark Hall!
March 2018 - Lab receives NIH R01 funding
Thanks to the NHLBI for supporting our work on controlled RNA delivery via EVs. UMD News Article
March 2018 - Dr. Jay receives NSF CAREER Award
Thanks to the NSF for supporting our work on therapeutic EV biomanufacturing. UMD News Article
March 2018 - Lab receives funding from the Rivkin Center for Ovarian Cancer
Thanks to the Rivkin Center for supporting our work on HER3-targeted therapeutics for ovarian cancer treatment.
March 2018 - Sonya Williams win Honors College Research Award
Congrats to Sonya for winning this award to support her BIOE Honors thesis research!
February 2018 - Jinan Oubaid wins Mtech Outstanding ASPIRE Student Research Award
Congrats to Jinan for winning 1 of 2 awards from Mtech recognizing her outstanding research contributions!
February 2018 - Natalie and Sonya win departmental awards
Two of our senior undergrad students received departmental awards, congrats and well deserved!
Fischell Outstanding Research Award: Natalie Livingston
Fischell Outstanding Citizen Award: Sonya Williams
UMD News Article
Fischell Outstanding Research Award: Natalie Livingston
Fischell Outstanding Citizen Award: Sonya Williams
UMD News Article
February 2018 - Sonya Williams awarded ASPIRE fellowship for Spring 2018
This award will enable Sonya to continue her protein therapeutics work in the lab until graduation this May. Congrats!
January 2018 - Dr. Jay named Associate Scientific Advisor for Science Translational Medicine
Early-career translational scientists are annually selected to serve for a period of 1 year to act as advisors for the journal and select and summarize research papers to be highlighted in the Editors' Choice section.
December 2017 - Anjana Jeyaram receives PhRMA Predoctoral Fellowship
Anjana was awarded a 2 year fellowship from the Pharmaceutical Research and Manufacturers Association (PhRMA) Foundation to study pharmaceutical and translational properties of extracellular vesicles! UMD News Article
November 2017 - Special Issue in Tissue Engineering on EVs
Tissue Engineering has published a Special Focus Issue on the Emerging Impact of Extracellular Vesicles on Tissue Engineering and Regeneration, guest edited by Steven M. Jay, PhD and Gordana Vunjak-Novakovic, PhD.
October 2017 - New publications on EVs
Congrats to Tek and Anjana for their new papers in Scientific Reports and AAPS Journal, respectively.
Congrats also to our collaborators Dr. Zhengguo Xiao and Dr. Catherine Fenselau!
Access Tek's paper here: Ethanol Induces Enhanced Vascularization Bioactivity of Endothelial Cell-Derived Extracellular Vesicles via Regulation of MicroRNAs and Long Non-Coding RNAs
Access Anjana's paper here: Preservation and Storage Stability of Extracellular Vesicles for Therapeutic Applications
With the Fenselau group: Ubiquitin Conjugation Probed by Inflammation in Myeloid-Derived Suppressor Cell Extracellular Vesicles
With the Xiao group: IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8+ T cells
Congrats also to our collaborators Dr. Zhengguo Xiao and Dr. Catherine Fenselau!
Access Tek's paper here: Ethanol Induces Enhanced Vascularization Bioactivity of Endothelial Cell-Derived Extracellular Vesicles via Regulation of MicroRNAs and Long Non-Coding RNAs
Access Anjana's paper here: Preservation and Storage Stability of Extracellular Vesicles for Therapeutic Applications
With the Fenselau group: Ubiquitin Conjugation Probed by Inflammation in Myeloid-Derived Suppressor Cell Extracellular Vesicles
With the Xiao group: IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8+ T cells
