February 2024 - Daniel Levy successfully defends PhD dissertation!
Congrats to Dan for becoming the 7th PhD graduate from the group!
January 2024 - Recent publication
Congrats to Dan and Talia for their recent paper in Current Opinion in Biotechnology.
Extracellular vesicles as therapeutics for inflammation and infection
Extracellular vesicles as therapeutics for inflammation and infection
January 2024 - STTR funding
The lab is excited to collaborate with Zymeron on a recently funded DOD STTR project!
December 2023 - Nick Pirolli successfully completes PhD proposal
Congrats to Nick for advancing to PhD candidacy!
September 2023 - Recent publications
Congrats to Nick and Louis for their recent papers in Biotechnology and Bioengineering and International Journal of Molecular Sciences, respectively.
High performance anion exchange chromatography purification of probiotic bacterial extracellular vesicles enhances purity and anti-inflammatory efficacy.
Chitosan Particles Complexed with CA5-HIF-1α Plasmids Increase Angiogenesis and Improve Wound Healing
High performance anion exchange chromatography purification of probiotic bacterial extracellular vesicles enhances purity and anti-inflammatory efficacy.
Chitosan Particles Complexed with CA5-HIF-1α Plasmids Increase Angiogenesis and Improve Wound Healing
August 2023 - Raith joins the lab
Welcome to Raith Nowak!
July 2023 - Recent publications
Congrats to Dan and Dipankar for their recent papers in Advanced Healthcare Materials and Biomaterials Science, respectively.
Induced Pluripotent Stem Cell-Derived Extracellular Vesicles Promote Wound Repair in a Diabetic Mouse Model via an Anti-Inflammatory Immunomodulatory Mechanism
Differentiation state and culture conditions impact neural stem/progenitor cell-derived extracellular vesicle bioactivity.
Induced Pluripotent Stem Cell-Derived Extracellular Vesicles Promote Wound Repair in a Diabetic Mouse Model via an Anti-Inflammatory Immunomodulatory Mechanism
Differentiation state and culture conditions impact neural stem/progenitor cell-derived extracellular vesicle bioactivity.
June 2023 - Lab receives funding from MSCRF
Thanks for the support of our work! Read more here: MSCRF funding
April 2023 - Recent publications
Congrats to Eli, Steph, and Dan for their recent papers in ncRNA, Cytotherapy, and Advanced Healthcare Materials, respectively.
Mesenchymal Stem Cell Culture within Perfusion Bioreactors Incorporating 3D-Printed Scaffolds Enables Improved Extracellular Vesicle Yield with Preserved Bioactivity
Assessment of anti-inflammatory bioactivity of extracellular vesicles is susceptible to error via media component contamination
Impact of storage conditions and duration on function of native and cargo-loaded mesenchymal stromal cell extracellular vesicles
Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy
Mesenchymal Stem Cell Culture within Perfusion Bioreactors Incorporating 3D-Printed Scaffolds Enables Improved Extracellular Vesicle Yield with Preserved Bioactivity
Assessment of anti-inflammatory bioactivity of extracellular vesicles is susceptible to error via media component contamination
Impact of storage conditions and duration on function of native and cargo-loaded mesenchymal stromal cell extracellular vesicles
Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy
March 2023 - Dan Levy named Ann G. Wylie Dissertation Fellow
Congrats to Dan for yet another award to support his thesis work in 2023-24!
January 2023 - Lab receives new FDA funding
Thanks to the FDA via the University of Maryland CERSI for supporting the lab!
September 2022 - Congrats to Steph Kronstadt on her successful PhD Thesis Defense!
Steph did awesome work over 4 years and is now headed off to Boston as an Innovation Fellow at Novartis!
August 2022 - Emily Powsner awarded NIH T32 Fellowship
Congrats to Emily on being selected for a fellowship position on the NIH Training Grant: Interdisciplinary Training Program in Cardiovascular Disease! This award via the National Heart, Lung, and Blood Institute (NHLBI) will support Emily's work on developing novel approaches to control EV vascularization bioactivity.
July 2022 - Talia Solomon joins the group
Welcome to Talia, a MD/PhD student and Clark Doctoral Fellow!
July 2022 - Dan Levy presents at Gordon Research Conference
Congrats to Dan on for being selected to present at both the Extracellular Vesicles GRS and GRC at Sunday River.
June 2022 - Congrats and farewell to Eli and Dipankar
We're happy to see Eli and Dipankar moving to the next stage of their careers. Eli will be pursuing postdoctoral training at the Weizmann Institute of Science in Israel while Dipankar will be a research analyst at The Block. Thanks for all your contributions to the lab!
May 2022 - Dan Levy awarded NIH T32 Fellowship
Congrats to Dan on being selected for a fellowship position on UMD's Host-Pathogen Interactions training grant from the National Institutes of Health! This award via the National Institute of Allergy and Infectious Diseases (NIAID) will support Dan's work on developing therapeutic approaches for sepsis.
April 2022 - Congrats to Dan Levy on his successful PhD Thesis Proposal!
Dan has advanced to PhD candidacy!
April 2022 - Dan Levy awarded Summer Research Fellowship
Congrats to Dan for this award to support his thesis work in 2022!
March 2022 - Steph Kronstadt named Ann G. Wylie Dissertation Fellow
Congrats to Steph for yet another award to support her thesis work in 2022!
February 2022 - Congrats to Dr. Eli Pottash on PhD Thesis Defense!
Eli becomes the fifth PhD student from the lab to successfully defend his thesis, congrats!
January 2022 - New publication in JBMR
Congrats to Louis on the publication of more of his thesis work on controlled delivery of EVs.
December 2021 - Steph Kronstadt named Mid-Career Clark Doctoral Fellow
Congrats to Steph for this award to support her thesis work in 2022!
November 2021 - Nick Pirolli awarded MPower Graduate Fellowship
Congrats to Nick for this award to support his cross-disciplinary research in creating live bacteria therapeutics for neurotherapy! Thanks to co-sponsor and collaborator Dr. Xiaofeng Jia.
November 2021 - New publication in iScience
Congrats to Dr. Wei Chao for his work investigating the role of miR-146a-5p in innate immunity and sepsis
September 2021 - Welcome Emily and Nick!
Emily Powsner and Nick Pirolli have joined the group as PhD students.
August 2021 - Lab awarded NIH R21 funding with collaborator Dr. Don DeVoe
This award from NHLBI supports research into novel EV isolation and loading techniques via microfabricated devices!
July 2021 - New publication in Nature Communications
Congrats to Dr. Joao Pedra for his work investigating the role of tick EVs in infection
June 2021 - Louis Born awarded NIH F30 Predoctoral Fellowship
Congrats to Louis on this award from NHLBI!
May 2021 - Congrats to Louis Born on PhD Thesis Defense!
Louis becomes the fourth PhD student from the lab to successfully defend his thesis, congrats! He will head in to the clinic to finish his medical training on the way to his MD/PhD!
April 2021 - New publications
Congrats to Louis, Steph, and incoming PhD student Nick Pirolli for their new papers in Advanced Healthcare Materials, Advanced Therapeutics, and Advanced Biology, respectively.
Access Louis's paper here: HOTAIR-Loaded Mesenchymal Stem/Stromal Cell Extracellular Vesicles Enhance Angiogenesis and Wound Healing
Access Steph's paper here: Therapeutic Potential of Extracellular Vesicles for Sepsis Treatment
Access Nick's paper here: Bacterial Extracellular Vesicles and the Gut-Microbiota Brain Axis: Emerging Roles in Communication and Potential as Therapeutics
Access Louis's paper here: HOTAIR-Loaded Mesenchymal Stem/Stromal Cell Extracellular Vesicles Enhance Angiogenesis and Wound Healing
Access Steph's paper here: Therapeutic Potential of Extracellular Vesicles for Sepsis Treatment
Access Nick's paper here: Bacterial Extracellular Vesicles and the Gut-Microbiota Brain Axis: Emerging Roles in Communication and Potential as Therapeutics
March 2021 - Louis Born awarded AHA Predoctoral Fellowship
Congrats to Louis on this award from the American Heart Association to support his research on EVs for wound repair!
February 2021 - Dan Levy awarded Cosmos Scholar Grant
Congrats to Dan on this award from the Cosmos Club Foundation to support his research on induced pluripotent stem cell EVs!
February 2021 - New publication in TINS
Congrats to Dr. Dipankar Dutta and MD/PhD student Niaz Khan for leading this comprehensive review on the roles and therapeutic potential of EVs in spinal cord injury published in Trends in Neurosciences
January 2021 - Lab receives funding from MIPS program
Thanks to the Maryland Technology Enterprise Institute (Mtech) for supporting our partnership with FiberCell Production Solutions to test engineered extracellular vesicles as wound healing therapeutics through the Maryland Industrial Partnerships (MIPS) program.