Biotherapeutic Development and Delivery LaboratorySteven M. Jay
Associate Professor, Fischell Department of Bioengineering University of Maryland, College Park 3116 A. James Clark Hall 301-405-2829 smjay@umd.edu |
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Our research aims to uncover new biological insights towards the design, production, and delivery of novel biotherapeutics and biomaterials. Our focus areas include extracellular vesicles (EVs, including exosomes), bacteria and live bacterial products such as bacterial extracellular vesicles (BEVs, including outer membrane vesicles (OMVs)), engineered protein therapeutics, and others. We strive to develop new drug delivery and biomanufacturing approaches using fundamental tools from both engineering and biology. Employing techniques in molecular biology, protein design, process engineering, and nanotechnology, we are primarily interested in developing new biotechnologies to address clinical needs in wound repair, cardiovascular disease, cancer, brain and spinal cord injuries, neurological diseases, osteoarthritis, and sepsis, among others. Overarching goals of the lab include developing therapeutics towards clinical translation and endowing trainees with the skills and knowledge necessary to become leaders in the biotechnology and pharmaceutical industries.
Recent Highlights
May 2022 - Dan Levy awarded NIH T32 Traineeship
March 2022 - Congrats to Steph Kronstadt on receiving the Ann G. Wylie Dissertation Fellowship!
February 2022 - Congrats to Dr. Eli Pottash on the successful defense of his PhD thesis!
November 2021 - Congrats to Nick Pirolli on receiving the MPower Graduate Fellowship!
August 2021 - Lab awarded new R21 funding from NIH with collaborator Dr. Don DeVoe
May 2021 - Congrats to Dr. Louis Born on the successful defense of his PhD thesis! Next up, finishing the MD at UMB.
March 2021 - Congrats to Louis Born on receiving both an AHA Predoctoral Fellowship and NIH F30 fellowship!
February 2021 - Congrats to Dan Levy on receiving the Cosmos Club Scholar Award!
January 2021 - Lab awarded Phase 1 funding from Maryland Industrial Partnerships (MIPS) program
August 2020 - Congrats to Rachel Lee on the successful defense of her MS thesis and position at FZata!
June 2020 - Vaani Shah recognized with Extraordinary Service Award
June 2020 - Dipankar Dutta awarded MSCRF Postdoctoral Fellowship
May 2020 - Steph Kronstadt awarded NIH T32 Traineeship
May 2020 - Lab awarded funding from FDA via University of Maryland CERSI
January 2020 - Lab awarded NIH R01 funding from NHLBI
December 2019 - New publication in Molecular Therapy
September 2019 - Congrats to Dr. Anjana Jeyaram on the successful defense of her PhD thesis and position at Novartis!
September 2019 - Lab awarded NIH RF1 funding from NIA
See more in News...
Recent Highlights
May 2022 - Dan Levy awarded NIH T32 Traineeship
March 2022 - Congrats to Steph Kronstadt on receiving the Ann G. Wylie Dissertation Fellowship!
February 2022 - Congrats to Dr. Eli Pottash on the successful defense of his PhD thesis!
November 2021 - Congrats to Nick Pirolli on receiving the MPower Graduate Fellowship!
August 2021 - Lab awarded new R21 funding from NIH with collaborator Dr. Don DeVoe
May 2021 - Congrats to Dr. Louis Born on the successful defense of his PhD thesis! Next up, finishing the MD at UMB.
March 2021 - Congrats to Louis Born on receiving both an AHA Predoctoral Fellowship and NIH F30 fellowship!
February 2021 - Congrats to Dan Levy on receiving the Cosmos Club Scholar Award!
January 2021 - Lab awarded Phase 1 funding from Maryland Industrial Partnerships (MIPS) program
August 2020 - Congrats to Rachel Lee on the successful defense of her MS thesis and position at FZata!
June 2020 - Vaani Shah recognized with Extraordinary Service Award
June 2020 - Dipankar Dutta awarded MSCRF Postdoctoral Fellowship
May 2020 - Steph Kronstadt awarded NIH T32 Traineeship
May 2020 - Lab awarded funding from FDA via University of Maryland CERSI
January 2020 - Lab awarded NIH R01 funding from NHLBI
December 2019 - New publication in Molecular Therapy
September 2019 - Congrats to Dr. Anjana Jeyaram on the successful defense of her PhD thesis and position at Novartis!
September 2019 - Lab awarded NIH RF1 funding from NIA
See more in News...
We are grateful to the following agencies/institutions/companies for generously supporting our work:
