Biotherapeutic Development and Delivery LaboratorySteven M. Jay
Assistant Professor, Fischell Department of Bioengineering University of Maryland, College Park 3131 Jeong H. Kim Engineering Building 301-405-2829 smjay@umd.edu |
|
Our research aims to uncover new biological insights towards the design and development of novel biotherapeutics (aka biopharmaceuticals), including proteins, extracellular vesicles (exosomes) and others. We also strive to develop new approaches to drug delivery and biomanufacturing using fundamental tools from both engineering and biology. Employing techniques in protein engineering, biomaterials, molecular biology and nanotechnology, we are primarily interested in projects at the interface of vascular or cancer biology and bioengineering with the objective of generating new therapies that can ultimately be translated to clinical use. An underpinning goal of the lab is to endow trainees with the skills and knowledge necessary to become leaders in the biotechnology and pharmaceutical industries.
Recent Highlights
October 2017 - Four new publications on EVs: Scientific Reports (x2), AAPS Journal, Journal of Proteome Research
July 2017 - Lab awarded funding for studying EVs in arthritis by Arthritis Foundation via Alpha Omicron Pi
June 2017 - Divya's paper on EV production published in Bioengineering and Translational Medicine
June 2017 - Lab awarded MPower seed funding for developing EVs for spinal cord injury treatment
June 2017 - Lab awarded funding from the Maryland Innovation Initiative for gene delivery for wound repair
May 2017 - John Schardt receives AAPS Fellowship to study cancer therapeutic development
April 2017 - New publication in ATVB highlighting cardiovascular drug delivery
March 2017 - John's paper published in Molecular Pharmaceutics on anti-cancer approaches
February 2017 - John Schardt receives 2017 PEGSummit Student Fellowship
December 2016 - Lab awarded funding from Elsa U. Pardee Foundation for cancer therapeutic development
October 2016 - Lab awarded funding from National Cancer Institute (NCI)
August 2016 - Dr. Jay named Cellular and Molecular Bioengineering Young Innovator
July 2016 - Tek's paper published in Cellular and Molecular Bioengineering on RNA interference via exosomes
June 2016 - Divya Patel awarded AHA Fellowship to study the exosome production microenvironment
See more in News...
Recent Highlights
October 2017 - Four new publications on EVs: Scientific Reports (x2), AAPS Journal, Journal of Proteome Research
July 2017 - Lab awarded funding for studying EVs in arthritis by Arthritis Foundation via Alpha Omicron Pi
June 2017 - Divya's paper on EV production published in Bioengineering and Translational Medicine
June 2017 - Lab awarded MPower seed funding for developing EVs for spinal cord injury treatment
June 2017 - Lab awarded funding from the Maryland Innovation Initiative for gene delivery for wound repair
May 2017 - John Schardt receives AAPS Fellowship to study cancer therapeutic development
April 2017 - New publication in ATVB highlighting cardiovascular drug delivery
March 2017 - John's paper published in Molecular Pharmaceutics on anti-cancer approaches
February 2017 - John Schardt receives 2017 PEGSummit Student Fellowship
December 2016 - Lab awarded funding from Elsa U. Pardee Foundation for cancer therapeutic development
October 2016 - Lab awarded funding from National Cancer Institute (NCI)
August 2016 - Dr. Jay named Cellular and Molecular Bioengineering Young Innovator
July 2016 - Tek's paper published in Cellular and Molecular Bioengineering on RNA interference via exosomes
June 2016 - Divya Patel awarded AHA Fellowship to study the exosome production microenvironment
See more in News...
We are grateful to the following agencies/institutions for generously supporting our work:
