August 2017 - Tek Lamichhane joins Medigen as Assistant Director
Congrats to Tek on his new job! Tek's contributions to the lab over 3+ years have been tremendous and he will be missed, but we wish him well in his new position.
July 2017 - Team MATRIX awarded funding from Alpha Omicron Pi
Congrats to Team MATRIX on receiving an Arthritis Foundation grant from the Alpha Omicron Pi Foundation to support their work studying potential therapeutic applications of EVs in osteoarthritis!
June 2017 - New Publication in Bioengineering and Translational Medicine
Divya's paper, entitled "Impact of Cell Culture Parameters on Production and Vascularization Bioactivity of Mesenchymal Stem Cell-Derived Extracellular Vesicles" was accepted in BioTM! This work, which was co-authored by Kelsey Gray and performed in collaboration with the laboratory of Kimberly Stroka at UMD, shows that cell passage and density impact the therapeutic and translational potential of MSC EVs. Great work all!
Access Divya's paper here: BioTM and the BioTM Buzz article featuring the work here: BioTM Buzz
Access Divya's paper here: BioTM and the BioTM Buzz article featuring the work here: BioTM Buzz
June 2017 - Lab receives funding from MPower Nervous System Injury and Neuroscience Initiative
This award with co-PI Junfang Wu from the University of Maryland School of Medicine enables study of exosome-based approaches to treatment of spinal cord injury.
June 2017 - Lab receives funding from Maryland Innovation Initiative
This award as a collaborator with Dr. John Harmon of Johns Hopkins University and Canton Biotechnologies facilitates the study of DNA delivery for wound repair.
May 2017 - John Schardt receives AAPS Graduate Student Fellowship
This award, 1 of only 6 awarded nationally, will support John's work on HER3 inhibitors for cancer therapy. Congrats! UMD News Article
May 2017 - Anjana Jeyaram advances to PhD candidacy
Congrats to Anjana, who successfully passed her PhD proposal examination and is now officially a PhD candidate!
April 2017 - New publication in ATVB
Collaborative work with the group of Yale Surgeon Dr. Alan Dardik published in Arteriosclerosis, Thrombosis, and Vascular Biology: CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation.
April 2017 - Divya Patel advances to PhD candidacy
Congrats to Divya, who successfully passed her PhD proposal examination and is now officially a PhD candidate!
April 2017 - Jinan Oubaid awarded ASPIRE scholarship for summer 2017
This award will enable Jinan to continue her protein therapeutics work in the lab. Congrats Jinan!
April 2017 - Sri Ayyagari defends BIOE Honors Thesis
Congrats to Sri, who successfully defended her BIOE Honors thesis! She becomes the first BIOE Honors awardee from the lab.
Sri will be pursuing a PhD in Biomedical Engineering at Case Western University!
Sri will be pursuing a PhD in Biomedical Engineering at Case Western University!
April 2017 - Natalie receives Honorable Mention in Goldwater Scholarship competition
Natalie Livingston was awarded a prestigious Honorable Mention in the Barry M. Goldwater Scholarship competition. Congrats Natalie!
March 2017 - New publication in Molecular Pharmaceutics
John's paper "Engineered Multivalency Enhances Affibody-Based HER3 Inhibition and Downregulation in Cancer Cells" was published in Molecular Pharmaceutics.
March 2017 - Sonya Williams receives Maryland Summer Scholars award
This award will support Sonya's work in the lab this summer!
February 2017 - John Schardt receives 2017 PEGSummit Student Fellowship
This award will support John's attendance at PEGS Boston, one of the premier protein engineering conferences in the world.
January 2017 - Eli joins the lab
Welcome to the newest PhD student in the group, Eli Pottash.
December 2016 - Lab receives funding from the Elsa U. Pardee Foundation
This award supports our work on HER3-targeted therapy in collaboration with Stan Lipkowitz at the NCI.
October 2016 - Lab receives funding from the National Cancer Institute (NCI)
This award, made through the University of Maryland Marlene and Stewart Greenebaum Cancer Center, supports our research on HER3-targeted therapies along with our collaborators Dr. Arif Hussain and Dr. Rena Lapidus.
August 2016 - Dr. Jay named Cellular & Molecular Bioengineering Young Innovator for 2016
Thanks to the hard work of everyone in the group, Dr. Jay was recognized with this honor alongside 10 talented colleagues. More info here: CAMB Young Innovators Issue
July 2016 - New Publication in Cellular and Molecular Bioengineering
Tek's paper "Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication" was published in Cellular and Molecular Bioengineering as part of the 2016 Young Innovators special issue.
June 2016 - Divya Patel receives AHA Predoctoral Fellowship
Divya was awarded a 2 year fellowship from the American Heart Association to study the effects of cellular mechanical microenvironment on EV biogenesis and vascularization bioactivity! UMD News Article
May 2016 - John Schardt receives AAPS Biotechnology Grad Student Award
John was awarded a Biotechnology Graduate Student Research Award from the American Association of Pharmaceutical Scientists (AAPS)! This award is sponsored by Eli Lilly and Company and included a travelship to the AAPS National Biotechnology Conference, where John gave an oral presentation on his project, as well as a plaque and cash prize. The Biotechnology Graduate Student Awards are designed to recognize excellence in graduate education in the field of pharmaceutical biotechnology.
John was also recently recognized with an honorable mention for the AAPS Graduate Student Fellowship, which includes a travelship to the AAPS National Meeting in Denver.
John was also recently recognized with an honorable mention for the AAPS Graduate Student Fellowship, which includes a travelship to the AAPS National Meeting in Denver.
April 2016 - Lab participates in 10th Fischell Festival
Several lab members attended and presented at the 10th Annual Fischell Festival celebrating the 10 year anniversary of the founding of our department. Thanks to the Fischell family for the continued support of our department
April 2016 - Natalie Livingston awarded HHMI fellowship
Natalie will continue her work on EVs with this award.
April 2016 - Sri Ayyagari receives Maryland Summer Scholars award
This award will support Sri's work in the lab this summer.
March 2016 - John Schardt passes PhD proposal examination
Congrats John!
September 2015 - New publication in Molecular Pharmaceutics
Tek's paper reports on crucial parameters that dictate the efficacy of extracellular vesicles for gene therapy.
July 2015 - Lab receives funding from National Cancer Institute (NCI)
This funding, made through the UMD-NCI Partnership for Integrative Cancer Research, will support John's work on designing novel HER3 inhibitors for cancer therapy along with collaborator Dr. Stanley Lipkowitz
June 2015 - Tek Lamichhane promoted to Research Assistant Professor
Congrats Tek!
May 2015 - Lab awarded Ralph E. Powe Junior Faculty Award
Dr. Jay received a 2015 Ralph E. Powe Junior Faculty Enhancement Award sponsored by Oak Ridge Associated Universities for our work on developing extracellular vesicle biotherapeutics for miRNA delivery.
April 2015 - Sonja awarded NIH Postdoctoral Fellowship
Dr. Sonja Sokic received an NIH NRSA F32 fellowship to fund her postdoctoral studies. This prestigious award will support Sonja's work examining ErbB signaling in vascularization.
March 2015 - Divya receives travel scholarship
Divya received a travel scholarship sponsored by the NSF to the ISEV 2015 Congress in April in Bethesda, MD to present her work involving extracellular vesicles for therapeutic vascularization.
March 2015 - Divya and Anjana join the group
Divya Patel and Anjana Jeyaram have joined the group as PhD students.
March 2015 - Douti and Alex awarded research fellowships
Two undergraduates in the lab have been awarded research fellowships. Alex George will enter the NIH Baccalaureate Program starting Summer 2015 prior to applying for graduate school. Lampouguin Douti received a summer research fellowship in nanomaterials at NIST. Both of these were highly competitive and great achievements.
February 2015 - Douti receives travel scholarship
Douti received a travel scholarship sponsored by NIH to the ISEV 2015 Congress in April in Bethesda, MD to present his work involving extracellular vesicle mechanobiology.
October 2014 - Tek and Douti receive travel awards
Tek and Douti each received travel awards to the TERMIS-AM conference in December in Washington DC to present their work involving extracellular vesicles.
July 2014 - Lab awarded UMD-UMB Seed Grant
The group was awarded a UMD-UMB Seed Grant in collaboration with Dr. Raj Sarkar at UMB to study extracellular vesicles for vascular therapy. Thanks to the UMD-UMB Seed Grant Program for the support.
June 2014 - New publication in Tissue Engineering Part B
Tek's review article, "Emerging roles for extracellular vesicles in tissue engineering and regenerative medicine", was published in Tissue Engineering Part B with contributions from everyone in the lab.
January 2014 - John joins the lab
John Schardt becomes the first Ph.D. student in the lab! John recently passed the Research Aptitude Exam with flying colors and has already been awarded a departmental prize for his fellowship application.
January 2014 - New publication in Endocrinology
A new article reporting the use of drug delivery technology to investigate metabolic homeostasis was published in the journal Endocrinology. This work was done in collaboration with corresponding author Dr. Chuhan Chung of Yale University.
January 2014 - Lab awarded UMD Tier 1 Grant
The group was awarded a Tier 1 seed grant from the University of Maryland to pursue studies of extracellular vesicles as drug delivery carriers. Thanks to UMD for the support.
November 2013 - Tek joins the lab
Dr. Tek Lamichhane has joined the lab as a research scientist. Tek will head up extracellular vesicle and molecular biology work in the lab and we look forward to his exciting contributions.
September 2013 - New publication in CIrculation Research
A new review article, "Protein engineering for cardiovascular therapeutics: untapped potential for cardiac repair", was published in the journal Circulation Research. This work was done with Dr. Richard T. Lee at Brigham and Women's Hospital.
August 2013 - BMES Innovation and Career Development Award to Dr. Jay
This award from the Biomedical Engineering Society (BMES) provides funds for travel and registration at the BMES Annual Fall Meeting in Seattle, WA. Thanks to BMES for the support.
July 2013 - New publication in Circulation
A new paper detailing the design of a novel protein that has potential as a therapeutic for cancer patients was recently published online in the journal Circulation. The article was also featured in an editorial in the same issue of the journal.
June 2013 - Jay Lab opens with NIH R00 award
The Jay Lab at UMD has officially opened and the lab has been awarded a Pathway to Independence R00 grant from the National Institutes of Health. This award will fund new research in protein engineering and drug delivery for improved wound healing in diabetes. Thanks to NIH for the continued support.
